Sufficiency of the number of segregating sites in the limit under finite-sites mutation.

作者: Arindam RoyChoudhury , John Wakeley

DOI: 10.1016/J.TPB.2010.05.003

关键词:

摘要: We show that the number of segregating sites is a sufficient statistic for scaled mutation parameter (θ)(θ) in limit as tends to infinity and there free recombination between sites. assume at each site zero such than total constant limit. Our results Watterson’s estimator maximum likelihood this case, but it estimates composite which different models. Some our hold when limited, because an unbiased, method-of-moments regardless rate. The quantity depends on details how mutations occur site.

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