Relationship between Exercise Parameters and Noninvasive Indices of Right Ventricular Function in Patients with Biventricular Circulation and Systemic Right Ventricle

作者: Keri M. Shafer , Nina Mann , Rebecca Hehn , Ana Ubeda Tikkanen , Anne Marie Valente

DOI: 10.1111/CHD.12248

关键词:

摘要: Objectives In patients with systemic right ventricles (RVs) in a biventricular circulation, exercise capacity and RV function often deteriorate over time echocardiographic assessment of is difficult. The purpose this study was to examine the relationship between determine which noninvasive imaging parameters correlate most closely capacity. Design Patients (D-loop transposition great arteries [TGA] after atrial switch procedure or physiologically “corrected” TGA) who underwent cardiopulmonary testing (CPX) (cardiac magnetic resonance [CMR] echocardiography [echo]) within 1 year CPX were identified. Regression analysis used evaluate variables indices ventricular function. Results We identified 92 149 encounters (mean age 31.0 years, 61% men, 70% D-loop meeting inclusion criteria. Statistically significant correlations % predicted peak oxygen uptake (%pVO2) ejection fraction (EF) (r = 0.29, P .0007), indexed end-systolic volume −0.25, .002), Tei index −0.22, .03) found. In without additional hemodynamically lesions, %pVO2 EF 0.37, .0007) −0.28, strengthened correlation emerged dP/dtic 0.31, .007). On multivariable analysis, only statistically (P .04). Conclusions In RVs CMR-derived RVEF echo-derived %pVO2. strongest predictor response.

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