Use of Nanoparticles in Brachytherapy – An Alternative for Enhancing Doses in Cancer Treatment

摘要: The aim of this study is to demonstrate that the use gold nanoparticles may enhance dose in tumour cells during brachytherapy. A Monte Carlo transport code, MCNPX was used estimate enhancement. high-intensity 192 Ir source design, for high dose-rate (HDR) brachytherapy simulation. located at uterus phantom proposed by Eckerman and Cristy, 1996. current considered three levels concentration within tumour: 7, 18 30 mg Au/g tissue assuming no presence outside tumour. enhancement factor region ranged from 5% 20% depending on radial distance level It concluded like Au are promising treatment because effectiveness enhancing doses cells. This effect has a substantial advantage reducing number daily fractions radiation tumour, compared with conventional treatment.