The contribution of classical conditioning to tolerance to the antinociceptive effects of ethanol.

作者: S.T. Tiffany , K.J. McCal , P.M. Maude-Griffin

DOI: 10.1007/BF00176489

关键词:

摘要: In rats, ethanol increases the latency of tail-flick reflex to radiant heat. Three experiments examined contribution classical conditioning acquisition tolerance this antinociception. Experiment 1 showed that antinociception produced by was dose dependent. The results 2 demonstrated rats exposed a series injections paired with distinctive environment developed 3, more pronounced in animals had been and tested than received nondistinctive environment. contrast previous reports literature, these show need not practice while intoxicated order develop tolerance. Additionally, data suggest may contribute antinociceptive effects ethanol.

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