Aneuploidy as a promoter and suppressor of malignant growth.
作者： Jason M. Sheltzer , Anand Vasudevan , Oluwadamilare A. Adebambo , Vishruth Girish , Erin L. Sausville
DOI: 10.1038/S41568-020-00321-1
关键词:
摘要: Aneuploidy has been recognized as a hallmark of tumorigenesis for more than 100 years, but the connection between chromosomal errors and malignant growth has remained …
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N G Irving, R H Reeves, R T Bronson, E C Akeson, C Schmidt, B S Harris, M T Davisson, Segmental trisomy as a mouse model for Down syndrome. Progress in Clinical and Biological Research. ,vol. 384, pp. 117- 133 ,(1993)
Loren S Michel, Vasco Liberal, Anupam Chatterjee, Regina Kirchwegger, Boris Pasche, William Gerald, Max Dobles, Peter K Sorger, VVVS Murty, Robert Benezra, None, MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells Nature. ,vol. 409, pp. 355- 359 ,(2001) , 10.1038/35053094
Harinder S. Garewal, Richard Sampliner, Yun Liu, Jeffrey M. Trent, Chromosomal rearrangements in Barrett's esophagus. A premalignant lesion of esophageal adenocarcinoma. Cancer Genetics and Cytogenetics. ,vol. 42, pp. 281- 286 ,(1989) , 10.1016/0165-4608(89)90096-4
Cheng-Zhong Zhang, Alexander Spektor, Hauke Cornils, Joshua M. Francis, Emily K. Jackson, Shiwei Liu, Matthew Meyerson, David Pellman, Chromothripsis from DNA damage in micronuclei Nature. ,vol. 522, pp. 179- 184 ,(2015) , 10.1038/NATURE14493
A.R.R. Maia, J. de Man, U. Boon, A. Janssen, J.-Y. Song, M. Omerzu, J.G. Sterrenburg, M.B.W. Prinsen, N. Willemsen-Seegers, J.A.D.M. de Roos, A.M. van Doornmalen, J.C.M. Uitdehaag, G.J.P.L. Kops, J. Jonkers, R.C. Buijsman, G.J.R. Zaman, R.H. Medema, Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model Annals of Oncology. ,vol. 26, pp. 2180- 2192 ,(2015) , 10.1093/ANNONC/MDV293
Darren J. Baker, Fang Jin, Karthik B. Jeganathan, Jan M. van Deursen, Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell. ,vol. 16, pp. 475- 486 ,(2009) , 10.1016/J.CCR.2009.10.023
Robin M. Ricke, Karthik B. Jeganathan, Jan M. van Deursen, Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation Journal of Cell Biology. ,vol. 193, pp. 1049- 1064 ,(2011) , 10.1083/JCB.201012035
Beth AA Weaver, Don W Cleveland, Does aneuploidy cause cancer Current Opinion in Cell Biology. ,vol. 18, pp. 658- 667 ,(2006) , 10.1016/J.CEB.2006.10.002
David A. Solomon, Jung-Sik Kim, Todd Waldman, Cohesin gene mutations in tumorigenesis: from discovery to clinical significance. Journal of Biochemistry and Molecular Biology. ,vol. 47, pp. 299- 310 ,(2014) , 10.5483/BMBREP.2014.47.6.092
Paul Kalitsis, Kerry J. Fowler, Belinda Griffiths, Elizabeth Earle, C. W. Chow, Kris Jamsen, K. H. Andy Choo, Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice Genes, Chromosomes and Cancer. ,vol. 44, pp. 29- 36 ,(2005) , 10.1002/GCC.20215