Further evidence for a complex system controlling feeding behavior

作者: D.J. Albert , L.H. Storlien , D.J. Wood , Gerard K. Ehman

DOI: 10.1016/0031-9384(70)90191-5

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摘要: Abstract The distribution of brain regions involved in feeding behavior was explored by disturbing synaptic conduction and interrupting neural pathways. Food consumption hungry rats significantly reduced blocking (with procaine hydrochloride) the lateral hypothalamus, anterolateral globus pallidus but not similar disturbances amygdala, preoptic area, posterolateral or caudate nucleus. A second experiment interrupted pathways with cuts order to examine organization circuitry region hypothalamus. severe aphagia adipsia followed coronal plane anterior posterior Less effects occurred sagittal hypothalamus through internal capsule. There only a transient effect area. These results suggest circuit which passes from brainstem longitudinally where separate bundles pass thalamus.

参考文章(35)
J.de Groot, The rat forebrain in stereotaxic coordinates North-Holland. ,(1959)
Y. Oomura, K. Kimura, H. Ooyama, T. Maeno, M. Iki, M. Kuniyoshi, Reciprocal Activities of the Ventromedial and Lateral Hypothalamic Areas of Cats Science. ,vol. 143, pp. 484- 485 ,(1964) , 10.1126/SCIENCE.143.3605.484
Philip Teitelbaum, Alan N. Epstein, The lateral hypothalamic syndrome: recovery of feeding and drinking after lateral hypothalamic lesions. Psychological Review. ,vol. 69, pp. 74- 90 ,(1962) , 10.1037/H0039285
B. G. Hoebel, P. Teitelbaum, Hypothalamic control of feeding and self-stimulation. Science. ,vol. 135, pp. 375- 377 ,(1962) , 10.1126/SCIENCE.135.3501.375
Rudolph H. de Jong, Irving H. Wagman, PHYSIOLOGICAL MECHANISMS OF PERIPHERAL NERVE BLOCK BY LOCAL ANESTHETICS. Anesthesiology. ,vol. 24, pp. 684- 695 ,(1963) , 10.1097/00000542-196309000-00019
Michael S. Levine, Norman Ferguson, Carol J. Kreinick, John W. Gustafson, J. S. Schwartzbaum, Sensorimotor dysfunctions and aphagia and adipsia following pallidal lesions in rats. Journal of Comparative and Physiological Psychology. ,vol. 77, pp. 282- 293 ,(1971) , 10.1037/H0031650
J. A. F. Stevenson, B. M. Box, D. G. Montemurro, EVIDENCE OF POSSIBLE ASSOCIATION PATHWAYS FOR THE REGULATION OF FOOD AND WATER INTAKE IN THE RAT Canadian Journal of Physiology and Pharmacology. ,vol. 42, pp. 855- 860 ,(1964) , 10.1139/Y64-095