On-demand d-modafinil may be an effective treatment option for lifelong premature ejaculation: a case report

摘要: Premature ejaculation (PE) is considered to be the most common form of male sexual dysfunction. Given that acute oral administration d-isomer modafinil (d-modafinil) can extend latency in rats without suppressing behaviour, effects on-demand d-modafinil treatment were examined on a 30-year-old patient with lifelong PE. The was instructed take 100 mg 3 h prior relation for four times and invited control visit. re-evaluated 2 weeks later. He reported his IELT increased 15 min. heartburn insomnia when he used first time; however, these symptoms transient did not recur after initial dose. Overall, considerable improvement noted feels much better treatment. Based this limited data, seems an effective men side mild case. Further randomised clinical trials are necessary elucidate therapeutic concept drug patients