The Question of Cycling of the Blood Neutrophil Concentrations and Pitfalls in the Statistical Analysis of Sampled Data

摘要: To test the hypothesis that there is normally a 14-21 day cycle in blood neutrophil concentration, of 13 normal male volunteers was sampled daily for 42 consecutive days. No evidence cyclic variation concentration found. The effect deleting four samples per week and interpolating values linearly or parabolically tested by power spectrum analysis, since this type analysis used studies which cycling interpolation missing found to introduce apparent cycling, results counts no different than obtained with series random numbers.