Going Viral with Fluorescent Proteins

摘要: Many longstanding questions about dynamics of virus-cell interactions can be answered by combining fluorescence imaging techniques with fluorescent protein (FP) tagging strategies. Successfully creating a FP fusion cellular or viral interest first requires selecting the appropriate FP. However, while architecture and localization often dictate suitability FP, FP's chemical physical properties must also considered. Here, we discuss challenges offer suggestions for identifying optimal FPs studying cell biology viruses.