Amino acid sequence and circular dichroism of Indian cobra (Naja naja naja) venom acidic phospholipase A2
作者： Florence F. Davidson , Edward A. Dennis
DOI: 10.1016/0167-4838(90)90095-W
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摘要: The full amino acid sequence of the acidic phospholipase A2 from Indian cobra (Naja naja naja) venom was determined and its tertiary structure examined by circular dichroism (CD). aligned with other sequences secreted snakes genus Naja, using progressive alignment method Feng Doolittle (J. Mol. Evol. (1987) 25, 351–360). primary Naja phospholipases shows up to 85% identity A2. CD studies indicate a 40–50% α-helical content in which resists denaturation at high temperature, or without chaotropic salts.
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