Biosynthesis and Distribution of Lipids

摘要: Publisher Summary This chapter provides an overview of lipid metabolism in mammalian cells from the point view subcellular synthesis, transport, and targeting lipid. It discusses available data, which indicate that different membranes have, to some extent, compositions. The various biosynthetic pathways fatty acid phospholipid biosynthesis are described, with emphasis on locations enzymes. principal product de novo tissue is palmitic acid. De takes place cytoplasm a cycle reactions catalyzed by multifunctional synthetase complex. Fatty acids can be modified desaturation introduce cis-double bonds elongation lengthen carboxyl end two carbons per step. also possible mechanisms responsible for transport between produce maintain describes three intracellular processes, may sorting within cell: (1) synthesis certain classes at they found, (2) transfer proteins, (3) process membrane flow.