Packed Red Blood Cell Transfusion Increases Regional Cerebral and Splanchnic Tissue Oxygen Saturation in Anemic Symptomatic Preterm Infants

摘要: Preterm infants often receive multiple packed red blood cell (PRBC) transfusions that are intended to improve tissue oxygen levels. Near-infrared spectroscopy (NIRS) monitors regional cerebral saturation (CrSO 2 ) and splanchnic (SrSO ). Before such technology can be employed in neonatal transfusion management, it must first established result an increase saturation. This prospective, observational study used NIRS determine if PRBC the CrSO SrSO of symptomatic anemic premature neonates. values were compared for 20-minute duration immediately before, during, after, 12 hours after transfusion. As a secondary objective, correlated with hemoglobin (Hgb) One-way analysis variance Pearson correlation statistical tests analysis. A statistically significant observed 30 subjects included : 62.8 ± 1.6, 65.6 1.7, 68.0 1.3, 67.6 1.4, P < 0.001 41.3 2.2, 46.7 3.0, 52.1 2.8, 48.2 2.5, 0.001). No was found between or Hgb values. identified increases preterm neonates has potential become incorporated into management paradigms.