摘要: Although a large number of compounds from wide variety plants have been tested for antitumor activity, none has played more vital role in cancer chemotherapy than the vinca alkaloids. These are present minute quantities plant Catharanthus roseus G. Don (Vinca rosea Linn.), commonly called periwinkle. this contains excess fifty alkaloids, only two these (vincristine and vinblastine) become established as important chemotherapeutic agents.