作者: Daniel B. Carr , Michael J. Cousins
DOI: 10.1007/978-1-4614-8441-7_60
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摘要: Pain has forever troubled humankind. Elucidation of nociceptive mechanisms and pathways, appreciation their diversity adaptability, have been essential to understanding pain. Anesthesiologists furthered such treatment, advanced the pain as a public health issue. During twentieth century, concepts post-injury sensitization hyperalgesia were developed, role humoral mediators recognized. The 1950s saw emergence anesthesia departments, facilitating research into acute chronic by specialists whose daily task originated with elimination during operations.