Calciphylaxis With Normal Renal and Parathyroid Function

摘要: Background Calciphylaxis is a life-threatening form of metastatic calcification-induced microvascular occlusion syndrome. Although traditionally observed in patients with end-stage renal disease and/or hyperparathyroidism, the development calciphylaxis “nontraditional” having both normal and parathyroid function has been reported. However, to date there no collective analysis identifying common patient characteristics potentially predisposing nontraditional patients. Observations A 58-year-old woman endometrial carcinoma developed extensive despite presence function. The resolved rapid diagnosis, supportive therapy, medical management. Analysis this case 13 previously reported cases identified following that highlight clinical situations calciphylaxis: hypoalbuminemia, malignant neoplasm, systemic corticosteroid use, anticoagulation warfarin sodium or phenprocoumon, chemotherapy, inflammation, hepatic cirrhosis, protein C S deficiency, obesity, weight loss, infection. Conclusions becoming increasingly observations from study may assist dermatologists diagnosis prompt initiation therapy for devastating disease.