The Mouse Idd2 Locus Is Linked to the Proportion of Immunoregulatory Double-Negative T Cells, a Trait Associated with Autoimmune Diabetes Resistance

作者: Roxanne Collin , Véronique Dugas , Adam-Nicolas Pelletier , Geneviève Chabot-Roy , Sylvie Lesage

DOI: 10.4049/JIMMUNOL.1400189

关键词:

摘要: … to DN T cell proportion and that a physiological increase in DN T … T cells may unravel key molecular targets to increase DN T cells in lymphoid organs, and thereby permit an increase in …

参考文章(60)
Evie Melanitou, Devasenan Devendra, Edwin Liu, Dongmei Miao, George S. Eisenbarth, Early and quantal (by litter) expression of insulin autoantibodies in the nonobese diabetic mice predict early diabetes onset. Journal of Immunology. ,vol. 173, pp. 6603- 6610 ,(2004) , 10.4049/JIMMUNOL.173.11.6603
S. Dejbachsh-Jones, P. Van Vlasselaer, James P Allison, S. Strober, S. Salimi, G. Duwe, Cloned natural suppressor cell lines express the CD3+CD4-CD8- surface phenotype and the alpha, beta heterodimer of the T cell antigen receptor. Journal of Immunology. ,vol. 143, pp. 1118- 1122 ,(1989)
Zhu-Xu Zhang, Liming Yang, Kevin J. Young, Barb DuTemple, Li Zhang, Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression Nature Medicine. ,vol. 6, pp. 782- 789 ,(2000) , 10.1038/77513
John J. Priatel, Oliver Utting, Hung-Sia Teh, TCR/Self-Antigen Interactions Drive Double-Negative T Cell Peripheral Expansion and Differentiation into Suppressor Cells The Journal of Immunology. ,vol. 167, pp. 6188- 6194 ,(2001) , 10.4049/JIMMUNOL.167.11.6188
Gilberto Filaci, Sabrina Bacilieri, Marco Fravega, Monia Monetti, Paola Contini, Massimo Ghio, Maurizio Setti, Francesco Puppo, Francesco Indiveri, Impairment of CD8+ T Suppressor Cell Function in Patients with Active Systemic Lupus Erythematosus The Journal of Immunology. ,vol. 166, pp. 6452- 6457 ,(2001) , 10.4049/JIMMUNOL.166.10.6452
Ram Pyare Singh, Antonio La Cava, Maida Wong, Fanny Ebling, Bevra H. Hahn, CD8+ T cell-mediated suppression of autoimmunity in a murine lupus model of peptide-induced immune tolerance depends on Foxp3 expression. Journal of Immunology. ,vol. 178, pp. 7649- 7657 ,(2007) , 10.4049/JIMMUNOL.178.12.7649
Maria Fritsch, Åsa Andersson, Karin Petersson, Fredrik Ivars, A TCR alpha chain transgene induces maturation of CD4- CD8- alpha beta+ T cells from gamma delta T cell precursors European Journal of Immunology. ,vol. 28, pp. 828- 837 ,(1998) , 10.1002/(SICI)1521-4141(199803)28:03<828::AID-IMMU828>3.0.CO;2-X
Christophe Viret, Charles A. Janeway, Self-Specific MHC Class II-Restricted CD4−CD8− T Cells That Escape Deletion and Lack Regulatory Activity Journal of Immunology. ,vol. 170, pp. 201- 209 ,(2003) , 10.4049/JIMMUNOL.170.1.201
Wenhao Chen, Megan S. Ford, Kevin J. Young, Myron I. Cybulsky, Li Zhang, Role of Double-Negative Regulatory T Cells in Long-Term Cardiac Xenograft Survival The Journal of Immunology. ,vol. 170, pp. 1846- 1853 ,(2003) , 10.4049/JIMMUNOL.170.4.1846