How to diagnose amyloidosis.

摘要: Amyloidosis is a rare but devastating condition caused by deposition of misfolded proteins as aggregates in the extracellular tissues body, leading to impairment organ function. High clinical suspicion required facilitate early diagnosis. Correct identification causal amyloid protein absolutely crucial for management order avoid misdiagnosis and inappropriate, potentially harmful treatment, assess prognosis, offer genetic counselling if relevant. This review summarises current evidence on which diagnosis subtyping amyloidosis based, outlines limitations various diagnostic techniques, particularly an Australian New Zealand context, discusses optimal strategies approach these patients. Recommendations are provided when suspect amyloidosis, what investigations required, well accurate amyloidosis.