Redox-signals and macrophage biology
作者： Andreas Weigert , Andreas von Knethen , Dominik Fuhrmann , Nathalie Dehne , Bernhard Brüne
DOI: 10.1016/J.MAM.2018.01.003
关键词:
摘要: Macrophages are known for their versatile role in biology. They sense and clear structures that contain exogenous or endogenous pathogen-associated molecular patterns. This process is tightly linked to the production of a mixture of potentially harmful oxidants and cytokines. Their inherent destructive behavior is directed against foreign material or structures of 'altered self', which explains the role of macrophages during innate immune reactions and inflammation. However, there is also another side of macrophages when they …
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