Three-dimensional stereology as a tool for evaluating bladder outlet obstruction.

作者: Jasper Van Der Wijk Jr , Jan Van Der Wijk Sr , Thomas Horn , Jens R. Nyengaard , Hassel Wijkstra

DOI: 10.1080/00365590701308511

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摘要: Objective. In a pilot study we evaluated whether implementation of novel 3D stereologic technique can prove that bladder outlet obstruction (BOO) is associated with morphologic changes in the wall. Material and methods. Ten males (mean age 69.7 years; range 58–84 years) lower urinary tract symptoms (LUTS) suggestive BOO five controls 48.6 43–53 without LUTS were studied. All participants underwent full examination, including determination International Prostate Symptom Score, laboratory analysis urodynamic evaluation. A cold-cup biopsy, taken during cystoscopy, was stereologically to determine smooth muscle cell volume fractions collagen using light electron microscopy. Results. The fraction higher patients than (probably because older). There no relation between Abrams–Griffiths number either interstitial or f...

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