Hormonal contraceptive regimens in the perimenopause

作者: Sarah M.R. Hardman , Ailsa E. Gebbie

DOI: 10.1016/J.MATURITAS.2009.05.001

关键词:

摘要: Perimenopausal women have low fertility but still need contraception if they are sexually active. They often co-existing menstrual problems and menopausal symptoms. No method of is contraindicated by age alone. In addition to highly effective contraception, hormonal methods offer non-contraceptive benefits which can improve quality life for perimenopausal women. Combined oral has been available many decades. The combined vaginal ring transdermal patch newer offering alternative delivery systems similar risk profiles preparations. New combinations containing naturally occurring estrogens in place the synthetic hormone ethinylestradiol now and, theory, could be safer. progestogen-only an excellent safety profile a range dosages suit all. Concerns regarding loss bone mineral density with injectable depot medroxyprogesterone acetate continue date there no evidence that this translates into higher fracture risk. Effective use any strongly dependent on good counselling support from healthcare professionals. Risks should explained absolute terms each individual woman, enabling her make informed choice evidence-based medicine not influenced ill-informed media publicity.

参考文章(92)
Øjvind Lidegaard, Birgitte Edström, Svend Kreiner, Oral contraceptives and venous thromboembolism: A case-control study Contraception. ,vol. 57, pp. 291- 301 ,(1998) , 10.1016/S0010-7824(98)00033-X
S Larsen, J Westergaard, E Bostofte, J Serup, Effectivity and acceptability of oral contraceptives containing natural and artificial estrogens in combination with a gestagen. A controlled double-blind investigation Acta Obstetricia et Gynecologica Scandinavica. ,vol. 60, pp. 203- 206 ,(1981)
, Hormones and cardiovascular health in women Human Reproduction Update. ,vol. 12, pp. 483- 497 ,(2006) , 10.1093/HUMUPD/DML028
P. Lahteenmaki, M. Haukkamaa, J. Puolakka, U. Riikonen, S. Sainio, J. Suvisaari, C. G. Nilsson, A. Prentice, Open randomised study of use of levonorgestrel releasing intrauterine system as alternative to hysterectomy. BMJ. ,vol. 316, pp. 1122- 1126 ,(1998) , 10.1136/BMJ.316.7138.1122
Writing Group for the Women's Health Initiative Investigators, Writing Group for the Women's Health Initiative Investigators, None, Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial JAMA. ,vol. 288, pp. 321- 333 ,(2002) , 10.1001/JAMA.288.3.321
Wong Mt, Singh K, The combined oral contraceptive pill in women over age forty. Annals Academy of Medicine Singapore. ,vol. 32, pp. 624- 631 ,(2003)