Methadone treatment, severe food insecurity, and HIV-HCV co-infection: A propensity score matching analysis

摘要: Abstract Background Severe food insecurity (FI) is common among individuals living with HIV-hepatitis C virus (HCV) co-infection. We hypothesize that the injection of opioids partly responsible for association between drug use and severe FI. Therefore, this analysis examines whether methadone maintenance treatment opioid dependence associated a lower risk Methods used biannual data from Canadian Co-infection Cohort (N = 608, 2012–2015). Methadone (exposure) was self-reported FI (outcome) measured using Household Food Security Survey Module. To quantify FI, we estimated an average effect on treated (marginal difference [RD]) propensity score matching. Results Among participants, 25% experienced in six months preceding first time-point analytical sample 5% concurrently reported receiving treatment. Injection outcome measurements much higher those who received (39% vs. 12%). 97% had injected their lifetimes. After matching, experiencing 12.3 percentage-points treatment, compared to are not RD = −0.123, 95% CI = −0.230, −0.015). Conclusions adjustment socioeconomic, sociodemographic, behavioural, clinical confounders, This finding suggests may mitigate vulnerable subset HIV-positive population.