The hydrophobic effect in reaction mechanism studies and in catalysis by artificial enzymes
作者： Ronald Breslow
DOI: 10.1002/POC.1037
关键词:
摘要: … Various tests3–5 made it clear that we were seeing hydrophobic acceleration by the water solvent. For one thing, methanol as solvent accelerated the reaction by only 4-fold, not 60-fold…
sci-hub.se 参考文章(32)
Lei Liu, Mary Rozenman, Ronald Breslow, Hydrophobic effects on rates and substrate selectivities in polymeric transaminase mimics. Journal of the American Chemical Society. ,vol. 124, pp. 12660- 12661 ,(2002) , 10.1021/JA028151K
Darryl C. Rideout, Ronald Breslow, Hydrophobic acceleration of Diels-Alder reactions Journal of the American Chemical Society. ,vol. 102, pp. 7816- 7817 ,(1980) , 10.1021/JA00546A048
Ronald Breslow, Richard V. Connors, Quantitative Antihydrophobic Effects as Probes for Transition State Structures. 1. Benzoin Condensation and Displacement Reactions Journal of the American Chemical Society. ,vol. 117, pp. 6601- 6602 ,(1995) , 10.1021/JA00129A028
Ronald Breslow, Kevin Groves, M. Uljana Mayer, Antihydrophobic Cosolvent Effects for Alkylation Reactions in Water Solution, Particularly Oxygen versus Carbon Alkylations of Phenoxide Ions† Journal of the American Chemical Society. ,vol. 124, pp. 3622- 3635 ,(2002) , 10.1021/JA012293H
Lei Liu, Ronald Breslow, Polymeric and dendrimeric pyridoxal enzyme mimics Bioorganic & Medicinal Chemistry. ,vol. 12, pp. 3277- 3287 ,(2004) , 10.1016/J.BMC.2004.03.062
M. Uljana Mayer, Ronald Breslow, ANTIHYDROPHOBIC EVIDENCE FOR THE SINGLE ELECTRON TRANSFER MECHANISM OF NUCLEOPHILIC SUBSTITUTION Journal of the American Chemical Society. ,vol. 120, pp. 9098- 9099 ,(1998) , 10.1021/JA982137J
Ronald Breslow, Richard Connors, Antihydrophobic Cosolvent Effects Detect Two Different Geometries for an SN2 Displacement and the Change to a Single-Electron-Transfer Mechanism in Related Cases Journal of the American Chemical Society. ,vol. 118, pp. 6323- 6324 ,(1996) , 10.1021/JA960868I
Wenjun Zhou, Lei Liu, Ronald Breslow, Transamination by polymeric enzyme mimics Helvetica Chimica Acta. ,vol. 86, pp. 3560- 3567 ,(2003) , 10.1002/HLCA.200390300
Ronald Breslow, Uday Maitra, On the origin of product selectivity in aqueous diels-alder reactions Tetrahedron Letters. ,vol. 25, pp. 1239- 1240 ,(1984) , 10.1016/S0040-4039(01)80122-2
Lei Liu, Ronald Breslow, A Potent Polymer/Pyridoxamine Enzyme Mimic Journal of the American Chemical Society. ,vol. 124, pp. 4978- 4979 ,(2002) , 10.1021/JA025895P