Outbreak of G2P[4] rotavirus gastroenteritis in a retirement community, Brazil, 2015: An important public health risk?

摘要: Abstract The present study described a group A rotavirus (RVA) outbreak in an age-care facility Brazil, using epidemiologic and molecular diagnostic methods. descriptive clinical, epidemiological environmental investigation was conducted. Stool samples were collected screened for RVA, Norovirus (NoV), Enteric Adenovirus 40/41 (AdV 40/41) Astrovirus (AstV) ELISA, RT-PCR, qRT-PCR, electron microscopy sequencing Outbreak occurred during 26th–29th October, 2015; 28 individuals affected (22 residents; 6 staff). attack rate 25.9% 8.5% among residents (median-age: 85.5 years) staff years), respectively. Female identified as the index case. RVA G2P[4] genotype detected 87.5% (7/8). Genetic analysis demonstrated that involved one single strain, suggesting common-source infection. should be considered outbreaks investigations residential facilities, raise question if current licensed vaccines children could also helpful elderly.