The Design of Experiments for Parameter Estimation

摘要: This paper is concerned with the design of experiments to estimate parameters in a model known form, which may be nonlinear parameters. problem was discussed detail by Box and Lucas for case where N, number experiments, equal p, The present work an extension cases N greater than p. Conditions are established under which, when multiple parameters, replication best p optimal experiments. Several chemical examples discussed; each instance, consists simply repeating points original An example also mentioned does not consist such replication.