Immunologically privileged sites in studies of polyoma tumor antigens.

摘要: Two polyoma tumors in mice were found to have a 1,000-fold increased transplantability if the IC or IT routes of inoculation are used instead SC. When virus-immune challenged by routes, degree demonstrable resistance was 10/sup 5/ and 4/ minimal transplantable numbers cells as compared 1/ SC route. Mice immunized with single dose x irradiated tumor later showed protection but not group. The ability vitro transformed tissue culture produce on inoculntion isologous adult most markedly enhanced whole-body irradiation, best results obtained made into animals. (auth)