Biocompatible oligomer-polymer compositions
作者： Richard L. Norton
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摘要: The present invention relates to biocompatible oligomer-polymer compositions for the in situ formation of implants, wherein implants release a bioactive agent, metabolite, or prodrug thereof, at controlled rate. sustained delivery system includes flowable composition containing and an implant thereof. may be injected into tissue whereupon it coagulates become solid gel, monolithic implant. biodegradable, thermoplastic polymer, end-capped oligomeric liquid,
lens.org 参考文章(13)
Christoph Volkel, Manuela Pfeiffer, Sabine Fricke, Ernst-Joachim Bormann, Matthias Schnabelrauch, Birgitt Beer, Sebastian Vogt, Biodegradable, injectable oligomer-polymer composition ,(2000)
Eric Dadey, Christopher M. Lindemann, Ruihong Li, Philippe Maria Clotaire Margaron, Sustained delivery formulations of rapamycin compounds ,(2008)
Phil Friden, F. Donald Roberts, Robert H. Reid, Charles E. McQueen, Jean A. Setterstrom, Ramasubbu Jevanthi, John E. van Hamont, Novel "burst-free" sustained release poly-(lactide/glycolide) mi crospheres ,(1996)
Paul Ricky Houston, Jeremy Corwin Wright, Guohua Chen, Lothar Walther Kleiner, Injectable depot compositions and uses thereof ,(2002)
X. D. Huang, S. H. Goh, Interpolymer Complexes through Hydrophobic Interactions: C60-End-Capped Poly(ethylene oxide)/Poly(methacrylic acid) Complexes Macromolecules. ,vol. 33, pp. 8894- 8897 ,(2000) , 10.1021/MA000614O
Friederike von Burkersroda, Luise Schedl, Achim Göpferich, Why degradable polymers undergo surface erosion or bulk erosion. Biomaterials. ,vol. 23, pp. 4221- 4231 ,(2002) , 10.1016/S0142-9612(02)00170-9
Andrew L. Ferguson, Pablo G. Debenedetti, Athanassios Z. Panagiotopoulos, Solubility and molecular conformations of n-Alkane chains in water Journal of Physical Chemistry B. ,vol. 113, pp. 6405- 6414 ,(2009) , 10.1021/JP811229Q
Harish Ravivarapu, Bhagya L. Chandrashekar, John Steven Garrett, Richard L. Dunn, Polymeric delivery formulations of leuprolide with improved efficacy ,(2001)
Guohua Chen, David T. Priebe, Short duration depot formulations ,(2003)
Luke E. Schallinger, James S. Stefely, David W. Schultz, Chester L. Leach, Daniel C. Duan, Craig A. Perman, Biocompatible compounds for pharmaceutical drug delivery systems ,(1998)