Risk of spinal cord dysfunction in patientsundergoing thoracoabdominal aortic replacement

摘要: The records of 150 consecutive patients underoingthoracoabdominal aortic replacement from 1980 to 1991 were retrospectively reviewed. There 89 men and 61 women; mean age was 67.8 years (range: 33 88 years). Since June 1989, a multimodality prospective perioperative protocol used reduce the risk spinal cord dysfunction. Ischemia is minimized by complete intercostal reimplantation whenever possible, cerebrospinal fluid drainage, maintenance proximal hypertension during cross-clamping. Spinal metabolism reduced moderate hypothermia, high-dose barbiturates, avoidance hyperglycemia. Reperfusion injury use mannitol, steroids, calcium channel blockers. Ninety-seven percent survived long enough for evaluation their neurologic function. dysfunction 6 108 (6%) in preprotocol group 0 42 (0%) (p A appears be effective reducing thoracoabdominal replacement.