Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures and kinetic modeling

作者: Jianlin Xu , Peifeng Tang , Andrew Yongky , Barry Drew , Michael C Borys

DOI: 10.1080/19420862.2018.1525262

关键词:

摘要: Temperature shift (TS) to a hypothermic condition has been widely used during protein production processes that use Chinese hamster ovary (CHO) cells. The effect of temperature on cell growth, meta...

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