The use of alteplase in a newborn with an aortic arch thrombus during extracorporeal membrane oxygenation.

摘要: We report a neonatal case of the use alteplase for lysis large aortic arch thrombus formed during extracorporeal membrane oxygenation support. Alteplase (0.1-0.15 mg/kg/hour) was infused thrombolysis, and meanwhile, unfractionated heparin administrated at 5-10 U/kg/hour anticoagulation purpose. successfully administered to this neonate after repair congenital diaphragmatic hernia on oxygenation, patient survived without apparent catastrophic long-term complications. It is reasonable consider therapy support in setting.