The production of hydroxyl and superoxide radicals by stimulated human neutrophils - measurements by EPR spectroscopy

作者: Martin R. Green , H.Allen O. Hill , Monika J. Okolow-Zubkowska , Anthony W. Segal

DOI: 10.1016/0014-5793(79)81123-0

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摘要: Neutrophilic polymorphonuclear leukocytes (neutrophils) consume considerably more oxygen in association with phagocytosis than the resting state. This extra respiration of [l] is not affected by inhibitors mitochondrial electron transport and distinct from process itself, which proceeds [2] normally under anaerobic conditions. The oxidase system appears to involve a novel cytochrome b [3,4] important [5] for microbicidal processes responsible killing certain bacteria. II I In

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