Chitosan/chondroitin sulfate hydrogels prepared in [Hmim][HSO4] ionic liquid.
作者： Cátia S Nunes , Kessily B Rufato , Paulo R Souza , Elizângela AMS de Almeida , Michael JV da Silva
DOI: 10.1016/J.CARBPOL.2017.04.073
关键词:
摘要: [Hmim][HSO4] ionic liquid (IL) and bio-renewable sources as chitosan (CHT) chondroitin sulfate (CS) were used to yield hydrogel-based materials (CHT/CS). The use of IL solubilize both polysaccharides was considered an innovative way based on "green chemistry" principle, aiming the production CHT/CS blended systems. hydrogels carried out in homogeneous medium from short dissolution times. characterized achieved with excellent stabilities (in 1.2-10pH range), larger swelling capacities, well devoid cytotoxicity towards normal VERO diseased HT29 cells. could be applied many technological purposes, like medical, pharmaceutical, environmental fields.
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