Rare cell analysis using sample splitting and dna tags
作者： Daniel Shoemaker , Zihua Wang , Darren Gray , Ravi Kapur , Mehmet Toner
DOI:
关键词:
摘要: The present invention provides systems, apparatuses, and methods to detect the presence of fetal cells when mixed with a population maternal in sample test abnormalities, e.g. aneuploidy. involves labeling regions genomic DNA each cell said different labels wherein label is specific quantifying labeled from sample. More particularly polymorphisms
glgoo.top参考文章(765)
Georgine Lamvu, Jeffrey A Kuller, Prenatal diagnosis using fetal cells from the maternal circulation. Western Journal of Medicine. ,vol. 159, pp. 308- 311 ,(1993)
Natasa Levicar, Myrtle Gordon, Method of fetal cell enrichment ,(2006)
T. M. Marteau, J. Kidd, R. Cook, M. Johnston, S. Michie, R. W. Shaw, J. Slack, Screening for down syndrome BMJ. ,vol. 297, pp. 1469- 1469 ,(2007) , 10.1136/BMJ.297.6661.1469-B
G. Fuhr, S. G. Shirley, Biological Application of Microstructures Topics in Current Chemistry. ,vol. 194, pp. 83- 116 ,(1998) , 10.1007/3-540-69544-3_4
Hiroshi Suemizu, Makoto Monnai, Yasuyuki Ohnishi, Masato Nakamura, Gene markers of tumor metastasis ,(2004)
Zihua Wang, Ravi Kapur, Mehmet Toner, Selection of cells using biomarkers ,(2007)
D. W. Bianchi, R. M. Bohmer, Dongka Zhen, Differential development of fetal and adult haemoglobin profiles in colony culture: isolation of fetal nucleated red cells by two-colour fluorescence labelling. British Journal of Haematology. ,vol. 103, pp. 351- 360 ,(1998)
M J Brisco, A A Morley, P J Sykes, E Hughes, J Condon, S H Neoh, Quantitation of targets for PCR by use of limiting dilution. BioTechniques. ,vol. 13, pp. 444- 449 ,(1992)
Kyoko Hida, Dhara N. Amin, Michael Klagsbrun, Method to prognose response to anti-egfr therapeutics ,(2006)