Are there risks for use of iron in cancer patients

摘要: Many cancer patients with anemia require recombinant human erythropoietins (EPO) to correct their anemia. Cancer is considered an inflammatory process and it associated the of chronic disease, secondary inflammation. Over last few years, concept functional iron deficiency has emerged as a consequence need administer iron, in one or another form, provide soluble, mobilized for formation new erythrocytes. (2004) reported treatment chemotherapy-related (n = 157) epoetin alfa shown that those who received i.v. (either bolus continuous infusion) had much better response than p.o. (p < 0.02). In more recent study (2007) ferric gluconate significantly improves versus oral anemic 187) receiving chemotherapy (73% vs 46%, p 0.009).With these data mind, expected use will increase dramatically among oncologists near future. But, administration safe? The reality metal, rather toxic substance (Table 1). Life planet Earth highly dependent on oxygen (O2) drive multiple energy storage processes. It well known combination oxygen, nature, notorious corrosive that, under physiologic conditions, yields harmful compounds such rust free radicals, (2003). Open image window