A Controlled Evaluation of the Protective Efficacy of Pneumococcal Vaccine for Patients at High Risk of Serious Pneumococcal Infections

作者: EUGENE D SHAPIRO , JOHN D CLEMENS

DOI: 10.7326/0003-4819-101-3-325

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摘要: The protective efficacy of pneumococcal vaccine against systemic infections in adults with the current indications for was evaluated a case-control study. Six (7%) 90 cases and 16 (18%) matched controls had received an odds ratio 0.33 (p less than 0.05). vaccine's 67%, which remained virtually unchanged after adjusting potential confounding variables. 77% patients at moderately increased risk infections, but 0% who were severely immunocompromised. 70% 0.05) all 55 years or older controlling addition to age. Pneumococcal confers substantial protection on elderly illnesses associated infections.

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