Mortality as an endpoint in atrial fibrillation1

摘要: The aim of this study was to evaluate the use mortality as an appropriate endpoint in studies atrial fibrillation. Almost none fibrillation trials has shown a significant difference among various treatment arms because are small, and many patient-years required show differences. Differences can be found when is used part combined meta-analyses trials. Some setting conditions predisposing high mortality, such heart failure, postmyocardial infarction, perioperative state for surgical procedures, have Nevertheless, role validating safety new therapies measure impact prognostic significance disease settings.