Immunological/physiological relationships in asthma: potential regulation by lung macrophages
作者： Leonard W. Poulter , George Janossy , Camillus Power , Seamus Sreenan , Conor Burke
DOI: 10.1016/0167-5699(94)90004-3
关键词:
摘要: There is now a consensus that T-cell-mediated inflammation and eosinophil activation in the bronchial wall contribute to pathogenesis of asthma. However, relationship between these immunopathological mechanisms observed physiological aberrations remain unclear. Here, Len Poulter colleagues identify links hyperresponsiveness, propose hypothesis for asthma which combination immunological abnormalities may result promotion disease. Furthermore, they suggest an integral factor prevention this process regulation T-cell reactivity by population immunosuppressive macrophages.
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