The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes.
作者： M-J Lee , S K Fried
DOI: 10.1038/IJO.2014.6
关键词:
摘要: The glucocorticoid receptor, not the mineralocorticoid plays dominant role in adipogenesis and adipokine production human adipocytes
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G Pöll-Jordan, W Schmidt, G Löffler, Adipose conversion of 3T3-L1 cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP. Journal of Biological Chemistry. ,vol. 265, pp. 15489- 15495 ,(1990) , 10.1016/S0021-9258(18)55422-3
Gang Yu, Z. Elizabeth Floyd, Xiying Wu, Teddi Hebert, Yuan-Di C. Halvorsen, Benjamin M. Buehrer, Jeffrey M. Gimble, Adipogenic differentiation of adipose-derived stem cells. Methods of Molecular Biology. ,vol. 702, pp. 193- 200 ,(2011) , 10.1007/978-1-61737-960-4_14
Hans Hauner, Thomas Skurk, Martin Wabitsch, Cultures of Human Adipose Precursor Cells Adipose Tissue Protocols. ,vol. 155, pp. 239- 247 ,(2001) , 10.1385/1-59259-231-7:239
J. Pairault, H. Green, A study of the adipose conversion of suspended 3T3 cells by using glycerophosphate dehydrogenase as differentiation marker Proceedings of the National Academy of Sciences of the United States of America. ,vol. 76, pp. 5138- 5142 ,(1979) , 10.1073/PNAS.76.10.5138
Laura L. Gathercole, Stuart A. Morgan, Iwona J. Bujalska, David Hauton, Paul M. Stewart, Jeremy W. Tomlinson, Regulation of Lipogenesis by Glucocorticoids and Insulin in Human Adipose Tissue PLoS ONE. ,vol. 6, pp. e26223- ,(2011) , 10.1371/JOURNAL.PONE.0026223
Stefan Engeli, Jana Böhnke, Mareike Feldpausch, Kerstin Gorzelniak, Ute Heintze, Jürgen Janke, Friedrich C. Luft, Arya M. Sharma, Regulation of 11β‐HSD Genes in Human Adipose Tissue: Influence of Central Obesity and Weight Loss Obesity Research. ,vol. 12, pp. 9- 17 ,(2004) , 10.1038/OBY.2004.3
Mi-Jeong Lee, Pornpoj Pramyothin, Kalypso Karastergiou, Susan K. Fried, Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity Biochimica et Biophysica Acta. ,vol. 1842, pp. 473- 481 ,(2014) , 10.1016/J.BBADIS.2013.05.029
H Hauner, G Entenmann, M Wabitsch, D Gaillard, G Ailhaud, R Negrel, E F Pfeiffer, Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium. Journal of Clinical Investigation. ,vol. 84, pp. 1663- 1670 ,(1989) , 10.1172/JCI114345
Ashley J. Peckett, David C. Wright, Michael C. Riddell, The effects of glucocorticoids on adipose tissue lipid metabolism Metabolism-clinical and Experimental. ,vol. 60, pp. 1500- 1510 ,(2011) , 10.1016/J.METABOL.2011.06.012
D. Kraus*, J. Jäger*, B. Meier, M. Fasshauer, J. Klein, Aldosterone inhibits uncoupling protein-1, induces insulin resistance, and stimulates proinflammatory adipokines in adipocytes. Hormone and Metabolic Research. ,vol. 37, pp. 455- 459 ,(2005) , 10.1055/S-2005-870240