Preservation of Memory With Conformal Avoidance of the Hippocampal Neural Stem-Cell Compartment During Whole-Brain Radiotherapy for Brain Metastases (RTOG 0933): A Phase II Multi-Institutional Trial
作者： Vinai Gondi , Stephanie L. Pugh , Wolfgang A. Tome , Chip Caine , Ben Corn
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摘要: Purpose Hippocampal neural stem-cell injury during whole-brain radiotherapy (WBRT) may play a role in memory decline. Intensity-modulated can be used to avoid conformally the hippocampal compartment WBRT (HA-WBRT). RTOG 0933 was single-arm phase II study of HA-WBRT for brain metastases with prespecified comparison historical control patients treated without avoidance.
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Edward A. Monaco, Amir H. Faraji, Oren Berkowitz, Phillip V. Parry, Uri Hadelsberg, Hideyuki Kano, Ajay Niranjan, Douglas Kondziolka, L. Dade Lunsford, Leukoencephalopathy after whole-brain radiation therapy plus radiosurgery versus radiosurgery alone for metastatic lung cancer. Cancer. ,vol. 119, pp. 226- 232 ,(2013) , 10.1002/CNCR.27504
Matthew K Schindler, M Elizabeth Forbes, Mike E Robbins, David R Riddle, Aging-dependent changes in the radiation response of the adult rat brain. International Journal of Radiation Oncology Biology Physics. ,vol. 70, pp. 826- 834 ,(2008) , 10.1016/J.IJROBP.2007.10.054
Vinai Gondi, Wolfgang A. Tomé, Minesh P. Mehta, Why Avoid the Hippocampus? A Comprehensive Review Radiotherapy and Oncology. ,vol. 97, pp. 370- 376 ,(2010) , 10.1016/J.RADONC.2010.09.013
Fred Hsu, Hannah Carolan, Alan Nichol, Fred Cao, Nimet Nuraney, Richard Lee, Ermias Gete, Frances Wong, Moira Schmuland, Manraj Heran, Karl Otto, Whole brain radiotherapy with hippocampal avoidance and simultaneous integrated boost for 1-3 brain metastases: a feasibility study using volumetric modulated arc therapy. International Journal of Radiation Oncology Biology Physics. ,vol. 76, pp. 1480- 1485 ,(2010) , 10.1016/J.IJROBP.2009.03.032
Ralph H.B. Benedict, David Schretlen, Lowell Groninger, Jason Brandt, Hopkins Verbal Learning Test—Revised: Normative data and analysis of inter-form and test–retest reliability. Clinical Neuropsychologist. ,vol. 12, pp. 43- 55 ,(1998) , 10.1076/CLIN.12.1.43.1726
Aaron H. Wolfson, Kyounghwa Bae, Ritsuko Komaki, Christina Meyers, Benjamin Movsas, Cecile Le Pechoux, Maria Werner-Wasik, Gregory M.M. Videtic, Yolanda I. Garces, Hak Choy, Primary Analysis of a Phase II Randomized Trial Radiation Therapy Oncology Group (RTOG) 0212: Impact of Different Total Doses and Schedules of Prophylactic Cranial Irradiation on Chronic Neurotoxicity and Quality of Life for Patients With Limited-Disease Small-Cell Lung Cancer International Journal of Radiation Oncology*Biology*Physics. ,vol. 81, pp. 77- 84 ,(2011) , 10.1016/J.IJROBP.2010.05.013
Peter S Eriksson, Ekaterina Perfilieva, Thomas Björk-Eriksson, Ann-Marie Alborn, Claes Nordborg, Daniel A Peterson, Fred H Gage, None, Neurogenesis in the adult human hippocampus Nature Medicine. ,vol. 4, pp. 1313- 1317 ,(1998) , 10.1038/3305
Jing Li, Soren M. Bentzen, Jialiang Li, Markus Renschler, Minesh P. Mehta, RELATIONSHIP BETWEEN NEUROCOGNITIVE FUNCTION AND QUALITY OF LIFE AFTER WHOLE-BRAIN RADIOTHERAPY IN PATIENTS WITH BRAIN METASTASIS International Journal of Radiation Oncology Biology Physics. ,vol. 71, pp. 64- 70 ,(2008) , 10.1016/J.IJROBP.2007.09.059
Vinai Gondi, Wolfgang A. Tome, James Marsh, Aaron Struck, Amol Ghia, Julius V. Turian, Søren M. Bentzen, John S. Kuo, Deepak Khuntia, Minesh P. Mehta, Estimated risk of perihippocampal disease progression after hippocampal avoidance during whole-brain radiotherapy: Safety profile for RTOG 0933 Radiotherapy and Oncology. ,vol. 95, pp. 327- 331 ,(2010) , 10.1016/J.RADONC.2010.02.030
Michelle L. Monje, Shinichiro Mizumatsu, John R. Fike, Theo D. Palmer, Irradiation induces neural precursor-cell dysfunction Nature Medicine. ,vol. 8, pp. 955- 962 ,(2002) , 10.1038/NM749