The prozone phenomenon in secondary syphilis.
作者： Taniguchi S , Osato K , Hamada T
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摘要: We describe a 37-year-old woman with secondary syphilis, in whom the prozone phenomenon (false-negative test undiluted specimens) occurred. The patient had been maintained on cyclosporine and prednisolone after renal transplantation. B-cell dysfunction induced by continuous immunosuppression may lead to higher non-treponemal serological titers. Non-treponemal testing should be repeated using serum dilutions prevent missing diagnosis of syphilis.
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