The impact of timely cancer diagnosis on age disparities in colon cancer survival in New Zealand

作者: Sophie Pilleron , Camille Maringe , Hadrien Charvat , June Atkinson , Eva JA Morris

DOI: 10.1101/2020.09.07.20189787

关键词:

摘要: Abstract Objective We described the role of patient-related and clinical factors on age disparities in colon cancer survival among patients aged 50-99 using New Zealand population-based registry data linked to hospitalization data. Design included new cases diagnosed between 1 January 2006 31 July 2017, followed up December 2019. these hospitalisation for five years before diagnosis. modelled effect at diagnosis, sex, deprivation, comorbidity, route diagnosis by stage (localized, regional, distant, missing). Results Net decreased as increased, notably advanced stages missing stage. The excess mortality older was minimal localised cancers, maximal during first six months regional 18 distant over three stages. pattern hazard varied according sex comorbidity with Conclusion present study shows that reflecting timeliness most affected difference middle-aged patients, probably impacting treatment strategy. Because high risk poor outcomes related efforts made improve earlier are likely help reduce Zealand.

参考文章(62)
Khokan C. Sikdar, James Dickinson, Marcy Winget, Factors associated with mode of colorectal cancer detection and time to diagnosis: a population level study BMC Health Services Research. ,vol. 17, pp. 7- 7 ,(2017) , 10.1186/S12913-016-1944-Y
J.S. Quirt, S. Nanji, X. Wei, J.A. Flemming, C.M. Booth, Is there a sex effect in colon cancer? Disease characteristics, management, and outcomes in routine clinical practice Current Oncology. ,vol. 24, pp. 15- 23 ,(2017) , 10.3747/CO.24.3410
Shaila J. Merchant, Sulaiman Nanji, Kelly Brennan, Safiya Karim, Sunil V. Patel, James J. Biagi, Christopher M. Booth, Management of stage III colon cancer in the elderly: Practice patterns and outcomes in the general population. Cancer. ,vol. 123, pp. 2840- 2849 ,(2017) , 10.1002/CNCR.30691
Jennifer N. Vega, Julie Dumas, Paul A. Newhouse, Cognitive Effects of Chemotherapy and Cancer-Related Treatments in Older Adults American Journal of Geriatric Psychiatry. ,vol. 25, pp. 1415- 1426 ,(2017) , 10.1016/J.JAGP.2017.04.001
Astrid Brousselle, Mylaine Breton, Lynda Benhadj, Dominique Tremblay, Sylvie Provost, Danièle Roberge, Raynald Pineault, Pierre Tousignant, Explaining time elapsed prior to cancer diagnosis: patients’ perspectives BMC Health Services Research. ,vol. 17, pp. 448- ,(2017) , 10.1186/S12913-017-2390-1
Daniel Brandeis, Samuele Cortese, Edmund Sonuga-Barke, Martin Holtmann, A Review of Current Evidence ,(2014)
Minjoung M. Koo, William Hamilton, Fiona M. Walter, Greg P. Rubin, Georgios Lyratzopoulos, Symptom Signatures and Diagnostic Timeliness in Cancer Patients: A Review of Current Evidence Neoplasia. ,vol. 20, pp. 165- 174 ,(2018) , 10.1016/J.NEO.2017.11.005
Claudia Allemani, Tomohiro Matsuda, Veronica Di Carlo, Rhea Harewood, Melissa Matz, Maja Nikšić, Audrey Bonaventure, Mikhail Valkov, Christopher J Johnson, Jacques Estève, Olufemi J Ogunbiyi, Gulnar Azevedo e Silva, Wan-Qing Chen, Sultan Eser, Gerda Engholm, Charles A Stiller, Alain Monnereau, Ryan R Woods, Otto Visser, Gek Hsiang Lim, Joanne Aitken, Hannah K Weir, Michel P Coleman, S Bouzbid, M Hamdi-Chérif, Z Zaidi, K Meguenni, D Regagba, S Bayo, T Cheick Bougadari, SS Manraj, K Bendahhou, A Fabowale, D Bradshaw, NIM Somdyala, I Kumcher, F Moreno, GH Calabrano, SB Espinola, B Carballo Quintero, R Fita, MC Diumenjo, WD Laspada, SG Ibañez, CA Lima, PCF De Souza, K Del Pino, C Laporte, MP Curado, JC de Oliveira, CLA Veneziano, DB Veneziano, MRDO Latorre, LF Tanaka, MS Rebelo, MO Santos, JC Galaz, M Aparicio Aravena, J Sanhueza Monsalve, DA Herrmann, S Vargas, VM Herrera, CJ Uribe, LE Bravo, LS Garcia, NE Arias-Ortiz, D Morantes, DM Jurado, MC Yépez Chamorro, S Delgado, M Ramirez, YH Galán Alvarez, P Torres, F Martínez-Reyes, L Jaramillo, R Quinto, J Castillo, M Mendoza, P Cueva, JG Yépez, B Bhakkan, J Deloumeaux, C Joachim, J Macni, R Carrillo, J Shalkow Klincovstein, R Rivera Gomez, E Poquioma, G Tortolero-Luna, D Zavala, R Alonso, E Barrios, A Eckstrand, C Nikiforuk, G Noonan, D Turner, E Kumar, B Zhang, FR McCrate, S Ryan, M MacIntyre, N Saint-Jacques, DE Nishri, CA McClure, KA Vriends, S Kozie, H Stuart-Panko, T Freeman, JT George, JT Brockhouse, DK O'Brien, A Holt, L Almon, S Kwong, C Morris, R Rycroft, L Mueller, CE Phillips, H Brown, B Cromartie, AG Schwartz, F Vigneau, GM Levin, B Wohler, R Bayakly, KC Ward, SL Gomez, M McKinley, R Cress, MD Green, K Miyagi, LP Ruppert, CF Lynch, B Huang, TC Tucker, D Deapen, L Liu, MC Hsieh, XC Wu, M Schwenn, ST Gershman, RC Knowlton, G Alverson, GE Copeland, S Bushhouse, DB Rogers, J Jackson-Thompson, D Lemons, HJ Zimmerman, M Hood, None, Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. The Lancet. ,vol. 391, pp. 1023- 1075 ,(2018) , 10.1016/S0140-6736(17)33326-3
Doris L. van Abbema, Marjan van den Akker, Maryska L. Janssen-Heijnen, Franchette van den Berkmortel, Ann Hoeben, Judith de Vos-Geelen, Frank Buntinx, Jos Kleijnen, Vivianne C.G. Tjan-Heijnen, Patient- and tumor-related predictors of chemotherapy intolerance in older patients with cancer: A systematic review. Journal of Geriatric Oncology. ,vol. 10, pp. 31- 41 ,(2019) , 10.1016/J.JGO.2018.04.001
Supriya G. Mohile, William Dale, Mark R. Somerfield, Mara A. Schonberg, Cynthia M. Boyd, Peggy S. Burhenn, Beverly Canin, Harvey Jay Cohen, Holly M. Holmes, Judith O. Hopkins, Michelle C. Janelsins, Alok A. Khorana, Heidi D. Klepin, Stuart M. Lichtman, Karen M. Mustian, William P. Tew, Arti Hurria, Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: Asco guideline for geriatric oncology Journal of Clinical Oncology. ,vol. 36, pp. 2326- 2347 ,(2018) , 10.1200/JCO.2018.78.8687