Lack of association between LincRNA-Pou3f gene expression and clinicopathological features in gastric cancer tissue

摘要: Abstract Emerging evidence supports the effective therapeutics for advanced or metastatic gastric cancers which have undergone little progress. Multiple pathophysiological process of lincRNA-POU3F3 and critical roles in cancer are not clearly defined. The aim this study was to evaluate expression LincRNA-POU3F3 compared adjacent healthy tissue gain further knowledge about aberrantly expressed value selected lincRNA. RNA extracted from 42 tumor samples paired normal tissues patients included present study. assessed using Real-time polymerase chain reaction. B2M used as an internal control. 2−ΔΔCq method determine fold changes (tumor vs. tissue). extent gene among (the mean age group 60.32 ± 14.185 years). level revealed no statistically significant difference between (P = 0.065). In order role cancer, associations transcript levels several clinicopathological features demonstrated stages I, III IV (P = 0.84), grade groups (P = 0.44), Helicobacter pylori (H. pylori) infection (P = 0.06) size (P = 0.71). Taken together, our results that at transcriptional had samples. Due this, it is a potential target diagnostic/therapeutic purposes.