Adsorption thermodynamics of acidic proline-rich human salivary proteins onto calcium apatites

摘要: The thermodynamics of adsorption four acidic proline-rich salivary proteins from their aqueous solutions onto hydroxyapatite (HA) and fluorapatite (FA) have been analyzed. Enthalpies entropies were derived isotherms at 37 degrees C 4 led to the unexpected conclusion that macromolecules studied is an endothermic process. Consequently, driven by increase in entropy. Most this originates adsorbate molecules, probably through disruption internal ion pairs, hydrogen bonds, displacement water molecules. Integral free energies (delta G) partial contributions adsorbent both calculated as a function coverages. For equal coverages (of each adsorbate), delta G lower with FA than HA. contribution adsorbate, although becomes significant saturation approached. differences various thermodynamic quantities are qualitatively related known structural features proteins. results important understanding role played oral environment.