Study of Porphyromonas gingivalis in periodontal diseases: A systematic review and meta-analysis.

摘要: Background: The mouth cavity hosts various types of anaerobic bacteria including Porphyromonas gingivalis, which causes periodontal inflammatory diseases. P. gingivalis is a gram-negative oral anaerobe and considered as main etiological factor in Several studies have reported relationship between individuals with diseases critical role this bacterium the pathogenesis present study aimed at estimating probability using meta-analysis. Methods: We searched several databases PubMed, Scopus, Google Scholar, Web Science to identify case-control addressing A total 49 reports published from different countries 1993 2014 were included study. I² (heterogeneity index) statistics calculated examine heterogeneity. Data analyzed STATA Version 11. Results: After detailed analysis selected articles, 5924 fulfilled inclusion criteria for healthy controls 2600 Mean±SD age 36.56±7.45 years. group 3356 patients mean 43.62±8.35 There was statistically significant difference controls; 9.24 (95% CI: 5.78 14.77; P = 0.000). In other word, there presence Conclusion: Analyzing results study, we found strong association This result suggests that another research needed further assess subject.