Headache and Other Head Pain

摘要: er only a few weeks before his untimely death on Feb 21, 1962. The first edition (1948) had marked milestone in our understanding of most common and important malady. Previous to the publication book, headache was regarded as troublesome accompaniment great number diseases abnormalities; however, mechanisms underlying its development were ill understood. Migraine, because high incidence dramatic prodromes, previously received extensive scrutiny, but diverse contradictory ideas still entertained concerning both nature causes. Of all men medicine, Harold Wolff contributed study clarification true significance. His monograph especially valuable circumstantial account remarkable observations which he associates made, over period 15 years, complicated aspects cerebral circulation rela¬ tion headache. new contains chap¬ ters summaries. Final editing page proof preparation con¬ venient index an unusually inform¬ ative bibliography supervised by Dr. Wolff's collaborator long-time associate, Helen Goodell. second possesses many features not included original monograph. It studies phenomena vasoconstriction later painful vasodilation lowered pain threshold characterize migraine attack. presents experiments that demon¬ strate headache-preventing effect carbon dioxide-oxygen mixtures other vasodilator agents. gives gain weight generalized edema are prodromes also localized ac¬ cumulates areas. By analysis latter, evidence is pre¬ sented noxious agents formed blood vessel walls perivascular tissue preceding influence local