Cell Configuration, Substratum and Growth Control

作者: Judah Folkman , Robert W. Tucker

DOI: 10.1016/B978-0-12-612984-7.50022-0

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摘要: Publisher Summary This chapter provides an overview of cell configuration, substratum, and growth control. Cell shape plays important role in While measurements appear tightly coupled to control, it should not be misconstrued that itself has anything do with the mechanism its effect. The experiments discussed suggest several different phenomena culture may linked because they are all mediated by shape. Thus, anchorage dependence, density dependent inhibition growth, response wounding, explained changes bring about Whatever which poly(HEMA) reduces adhesivity polystyrene, cells respond a change There is link between tumor angiogenesis. Because seem able escape controls on reach densities level crowdedness attainable normal cells. cost such high appears greatly increased demand for oxygen nutrients, means diffusing away wastes.

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