摘要: The traditional "aspirin first" approach to the treatment of osteoarthritis and rheumatoid arthritis is undergoing serious reappraisal. Aspirin acetaminophen are equipotent in their analgesic efficacy; however, aspirin associated with a higher incidence side effects. Acetaminophen should therefore be used as first-line therapy for since reduction pain primary therapeutic objective. Analgesic doses (up 3,900 mg per day) do not produce an anti-inflammatory effect thus beneficial arthritis. Only high (4 6 g sustained period effect. Since many patients cannot tolerate long-term use aspirin, it may preferable initiate one newer nonsteroidal drugs.
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