LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells

作者: H Xiong , Z Ni , J He , S Jiang , X Li

DOI: 10.1038/ONC.2016.521

关键词:

摘要: … HULC is the first identified lncRNA that is specifically … role in liver carcinogenesis and acts as an oncogenic lncRNA. However… of the liver-specific long noncoding RNA HULC by the IGF2 …

参考文章(40)
Tao Luo, Jing Fu, An Xu, Bo Su, Yibing Ren, Ning Li, Junjie Zhu, Xiaofang Zhao, Rongyang Dai, Jie Cao, Bibo Wang, Wenhao Qin, Jinhua Jiang, Juan Li, Mengchao Wu, Gensheng Feng, Yao Chen, Hongyang Wang, PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression. Autophagy. ,vol. 12, pp. 1355- 1371 ,(2016) , 10.1080/15548627.2015.1034405
Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray, Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer. ,vol. 136, ,(2015) , 10.1002/IJC.29210
Bo Tang, Fang Tang, Bo Li, Shengguang Yuan, Qing Xu, Stephen Tomlinson, Junfei Jin, Wei Hu, Songqing He, High USP22 expression indicates poor prognosis in hepatocellular carcinoma Oncotarget. ,vol. 6, pp. 12654- 12667 ,(2015) , 10.18632/ONCOTARGET.3705
Qian Li, Yao Fang, Pan Zhu, Chun-yan Ren, Hai Chen, Jiang Gu, Yin-ping Jia, Kun Wang, Wen-de Tong, Wei-jun Zhang, Jing Pan, Dong-shui Lu, Bin Tang, Xu-hu Mao, Burkholderia pseudomallei survival in lung epithelial cells benefits from miRNA-mediated suppression of ATG10. Autophagy. ,vol. 11, pp. 1293- 1307 ,(2015) , 10.1080/15548627.2015.1058474
Guanglin Qiu, Xuqi Li, Xiangming Che, Chao Wei, Shicai He, Jing Lu, Zongliang Jia, Ke Pang, Lin Fan, SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment FEBS Letters. ,vol. 589, pp. 2034- 2042 ,(2015) , 10.1016/J.FEBSLET.2015.05.042
Monika Hämmerle, Tony Gutschner, Hannah Uckelmann, Sevim Ozgur, Evgenij Fiskin, Matthias Gross, Britta Skawran, Robert Geffers, Thomas Longerich, Kai Breuhahn, Peter Schirmacher, Georg Stoecklin, Sven Diederichs, Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1) Hepatology. ,vol. 58, pp. 1703- 1712 ,(2013) , 10.1002/HEP.26537
Pedro J. Batista, Howard Y. Chang, Long Noncoding RNAs: Cellular Address Codes in Development and Disease Cell. ,vol. 152, pp. 1298- 1307 ,(2013) , 10.1016/J.CELL.2013.02.012
Jianrui Song, Zengqiang Qu, Xianling Guo, Qiudong Zhao, Xue Zhao, Lu Gao, Kai Sun, Feng Shen, Mengchao Wu, Lixin Wei, Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells. Autophagy. ,vol. 5, pp. 1131- 1144 ,(2009) , 10.4161/AUTO.5.8.9996
Xiao-Yong Zhang, Maya Varthi, Stephen M. Sykes, Charles Phillips, Claude Warzecha, Wenting Zhu, Anastasia Wyce, Alan W. Thorne, Shelley L. Berger, Steven B. McMahon, The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Molecular Cell. ,vol. 29, pp. 102- 111 ,(2008) , 10.1016/J.MOLCEL.2007.12.015
Hashem B. El-Serag, Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma Gastroenterology. ,vol. 142, pp. 1264- 1273.e1 ,(2012) , 10.1053/J.GASTRO.2011.12.061