PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression.

作者: Tao Luo , Jing Fu , An Xu , Bo Su , Yibing Ren

DOI: 10.1080/15548627.2015.1034405

关键词:

摘要: Although autophagy is most critical for survival of cancer cells, especially in fast-growing tumors, the mechanism remains to be fully characterized. Herein we report that PSMD10/…

参考文章(50)
Angela Gauthier, Mitchell Ho, Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update Hepatology Research. ,vol. 43, pp. 147- 154 ,(2013) , 10.1111/J.1872-034X.2012.01113.X
Hiroaki Higashitsuji, Katsuhiko Itoh, Toshikazu Nagao, Simon Dawson, Kohsuke Nonoguchi, Tsuneo Kido, R. John Mayer, Shigeki Arii, Jun Fujita, Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas Nature Medicine. ,vol. 6, pp. 96- 99 ,(2000) , 10.1038/71600
Toumy Guettouche, Frank Boellmann, William S Lane, Richard Voellmy, Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress. BMC Biochemistry. ,vol. 6, pp. 4- 4 ,(2005) , 10.1186/1471-2091-6-4
Jens Füllgrabe, Melinda A. Lynch-Day, Nina Heldring, Wenbo Li, Robert B. Struijk, Qi Ma, Ola Hermanson, Michael G. Rosenfeld, Daniel J. Klionsky, Bertrand Joseph, The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy Nature. ,vol. 500, pp. 468- 471 ,(2013) , 10.1038/NATURE12313
Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi, Brett A. McCray, Gillian P. Ritson, Natalia B. Nedelsky, Stephanie L. Schwartz, Nicholas A. DiProspero, Melanie A. Knight, Oren Schuldiner, Ranjani Padmanabhan, Marc Hild, Deborah L. Berry, Dan Garza, Charlotte C. Hubbert, Tso-Pang Yao, Eric H. Baehrecke, J. Paul Taylor, HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS Nature. ,vol. 447, pp. 859- 863 ,(2007) , 10.1038/NATURE05853
Trond Lamark, Terje Johansen, Autophagy: links with the proteasome Current Opinion in Cell Biology. ,vol. 22, pp. 192- 198 ,(2010) , 10.1016/J.CEB.2009.11.002
C. Settembre, C. Di Malta, V. A. Polito, M. G. Arencibia, F. Vetrini, S. Erdin, S. U. Erdin, T. Huynh, D. Medina, P. Colella, M. Sardiello, D. C. Rubinsztein, A. Ballabio, TFEB links autophagy to lysosomal biogenesis. Science. ,vol. 332, pp. 1429- 1433 ,(2011) , 10.1126/SCIENCE.1204592
Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita, Takahiro Kodama, Hinako Tsunematsu, Takuya Miyagi, Atsushi Hosui, Hisashi Ishida, Tomohide Tatsumi, Tatsuya Kanto, Naoki Hiramatsu, Naonobu Fujita, Tamotsu Yoshimori, Norio Hayashi, Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. International Journal of Cancer. ,vol. 131, pp. 548- 557 ,(2012) , 10.1002/IJC.26374
Jianrui Song, Zengqiang Qu, Xianling Guo, Qiudong Zhao, Xue Zhao, Lu Gao, Kai Sun, Feng Shen, Mengchao Wu, Lixin Wei, Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells. Autophagy. ,vol. 5, pp. 1131- 1144 ,(2009) , 10.4161/AUTO.5.8.9996
Jing Fu, Yao Chen, Jie Cao, Tao Luo, You-Wen Qian, Wen Yang, Yi-Bin Ren, Bo Su, Guang-Wen Cao, Yuan Yang, Yi-Qun Yan, Feng Shen, Meng-Chao Wu, Gen-Sheng Feng, Hong-Yang Wang, p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3‐kinase/AKT/hypoxia‐inducible factor‐1α pathways Hepatology. ,vol. 53, pp. 181- 192 ,(2011) , 10.1002/HEP.24015