Blood-Brain Barrier Disruption with Focused Ultrasound Enhances Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment
作者： Hao-Li Liu , Mu-Yi Hua , Pin-Yuan Chen , Po-Chun Chu , Chia-Hsin Pan
关键词:
摘要: This study demonstrates that focused US treatment serves a noninvasive method for the targeted delivery of 1,3-bis (2-chloroethyl)-1-nitrosourea through blood-brain barrier so chemotherapeutic drug dosage can be increased specifically in tumor region, significantly suppressing growth and prolonging animal survival.
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