作者: Fan Xianqun , Wen Xuyang , Ge Shengfang , Chai Peiwei , Zhang He
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摘要: The invention discloses application of EZH2 (enhancer zeste homolog 2) inhibitor compounds in the preparation drugs for treating eye melanoma; include GSK503, GSK343, EPZ005687 and EPZ-6438, having molecular formulas C31H38N6O2, C31H39N7O2, C34H44N4O4 C32H37N5O3, structural which are shown description. is intended to provide novel targets clinical treatment melanoma, effectiveness improved, ball extraction rate reduced, vision prognosis patient a field exploited unprecedentedly.